Latisse® is the only FDA-approved prescription treatment for inadequate or sparse eyelashes, a condition known as eyelash hypotrichosis.

Its active ingredient is bimatoprost 0.03%, a prostaglandin analog that was originally developed to treat glaucoma under the brand name Lumigan®.

How Latisse Works

Latisse works by affecting the natural eyelash growth cycle. It:

  • Extends the anagen (growth) phase, allowing lashes to grow longer.
  • Increases the number of hairs in the growth phase, making lashes appear fuller.
  • Enhances pigment production, resulting in naturally darker lashes.

Most people begin noticing results within 4 to 8 weeks, with full results typically appearing after 12 to 16 weeks of consistent use.

What Results Can You Expect?

With nightly application, patients can expect:

  • Noticeably longer lashes
  • Increased thickness and density
  • A naturally darker appearance, even without mascara

Keep in mind that results require ongoing use. If you stop applying Latisse, your eyelashes will gradually return to their original appearance over the next few months.

Prescription Options

Latisse®

Latisse is the FDA-approved option specifically indicated for eyelash growth.

Benefits include:

  • FDA-approved for eyelash hypotrichosis
  • Includes sterile, single-use applicators
  • Supported by extensive clinical research
  • Considered the gold standard for lash growth treatment

Its main drawback is that it is typically the most expensive option.

Lumigan® (Off-Label Use)

Lumigan contains the same active ingredient, bimatoprost, usually in concentrations of 0.01% or 0.03%.

Although FDA-approved for glaucoma—not eyelash growth—it is sometimes prescribed off-label for cosmetic lash enhancement.

Advantages include:

  • Often more affordable than Latisse
  • Contains the same active ingredient

However:

  • It is not packaged specifically for cosmetic use.
  • Patients must use a separate applicator.
  • Proper application requires additional patient education.

Compounded Lash Serum Options

Compounded lash serums have become increasingly popular in aesthetic practices because they allow providers to customize treatment based on a patient's needs.

Common compounded formulations include:

  • Bimatoprost 0.03%
  • Bimatoprost with hyaluronic acid
  • Bimatoprost with peptides for added conditioning
  • Lower-dose bimatoprost (0.01%–0.02%) for patients with sensitive eyes

Safety and Possible Side Effects

Latisse is generally well tolerated, but patients should be aware of potential side effects, including:

  • Mild redness or itching along the lash line
  • Temporary darkening of the eyelid skin
  • Rare changes in iris pigmentation (primarily associated with intraocular use but still worth discussing)

Application Tips

For the safest and most effective results:

  • Apply only to the upper lash line.
  • Use a clean, sterile applicator each night.
  • Do not apply directly into the eye.
  • Remove contact lenses before application if instructed by your provider.

Our Approach

We offer both FDA-approved and customized treatment options based on your goals, sensitivity, and budget.

For patients seeking the gold-standard treatment, Latisse® remains our preferred recommendation. For others, a compounded bimatoprost formula may provide excellent results while offering additional conditioning ingredients and greater flexibility.

Lizzie Brennan

Author

Lizzie Brennan, PA-C is a board-certified Physician Assistant with more than 20 years of medical experience and over a decade specializing in dermatology. As the founder of WellWell, she combines expert skin care with evidence-based metabolic medicine to help patients feel confident inside and out. Lizzie is passionate about making high-quality dermatologic care and medical weight loss accessible through convenient telehealth and personalized, patient-centered treatment.